With AbbVies acquisition of Syndesi, we aim to advance the research of a novel, first-in-class asset for the potential treatment of cognitive impairment associated with neuropsychiatric and neurodegenerative disorders.. Novo Holdings is a private limited liability company wholly owned by the Novo Nordisk Foundation. Copenhagen, Denmark - Novo Holdings, a leading international life sciences investor, today announces that its portfolio company Syndesi Therapeutics ('Syndesi') has been acquired by AbbVie (NYSE: ABBV) for up to US$1 billion in total deal value with US$ 130 million upfront. Request Profile Update Download Data Home Profiles Pharmaceutical Company Europe Syndesi Therapeutics Syndesi Therapeutics Details Syndesi Therapeutics Contact Information Get News Stories Delivered to Your Inbox Your Email: Join Today In the life science sector, SRIW is investor in more than 30 companies such as I.B.A., Celyad, or Ogeda of which it recently exited. . UCBs Neuroscience researchers in Belgium have designed a unique class of novel SV2A modulators. Company Presentation . Syndesi Therapeutics is developing molecules that uniquely modulate the synaptic vesicle protein SV2A, which plays a central role in synaptic transmission (the communication between neurons in the brain). Syndesi will build on a rich legacy of work by UCB to further develop these novel SV2A modulators to investigate their potential to improve cognition in diseases such as Alzheimers Disease, other dementias and cognitive impairment associated with schizophrenia. Fountain Healthcare Partners (www.fh-partners.com) is a life science focused venture capital fund with 176 million ($200 million) under management. UCB, Brussels, Belgium (www.ucb.com) is a global biopharmaceutical company focused on the discovery and development of innovative medicines and solutions to transform the lives of people living with severe diseases in immunology and neurology. The lead molecule, SDI-118, is a small molecule currently in Phase 1b studies, which is being evaluated to target nerve terminals to enhance synaptic efficiency. Four years after spinning out from Belgium's UCB, Syndesi Therapeutics and its SV2A modulator programme has been bought. IMPROVING THE LIVES OF PATIENTS AND THEIR FAMILIES. info@prilenia.com. Regulating the synaptic transmission is a promising approach to treat Alzheimer's disease and other disorders with cognitive impairment. Milestone payments could bring shareholders of the biotech up to $870. More. OUR PIPELINE JOIN US TODAY Clinical studies at UCB: How are medicines made and tested? MT . Do not sell my information, Bain Capital-Backed Emalex Bio Lands $250M for Pivotal Test of Tourette Drug, How To Create Digital Health Apps That Serve as Useful Tools (Not Unnecessary Work), Why Digital Health Collaborations Are the Future of Medtech, Rubiuss New Cell Therapy Strategy Runs Out of Time & Money; Workforce Is Cut by 82%, Startup Founded by Brown Undergrads Raises $14M to Improve Care for Vulnerable Seniors, AMA: CMS 2023 Physician Fee Schedule Would Create Financial Instability, Carta Healthcare Rakes in $20M with Hopes of Selling its Tech to More Hospitals, CVS, Walgreens Will Pay $10 Billion Total To Settle Opioid-Related Lawsuits. Lead Syndesi drug candidate SDI-118 came from UCB research of molecules that regulate SV2A, but to improve cognition rather than stop epileptic seizures. All rights reservedLast updated on:April, 07, 2022, Syndesi Therapeutics is based in Belgium and will leverage UCBs neurology expertise in modulating the synaptic vesicle protein SV2A. We make long term investments in early stage companies in the US and Europe. The company's drugs can modulate the synaptic vesicle protein to handle the transmission between neurons in the brain to effectively treat Alzheimer's and other disorders with cognitive impairment, enabling healthcare providers to treat these diseases with the right therapy at their disposal. You need JavaScript enabled to view it. On March 1, 2022 AbbVie (NYSE: ABBV) reported it has completed the acquisition of Syndesi Therapeutics SA, which will help to expand AbbVie's neuroscience portfolio (Press release, AbbVie, MAR 1, 2022, View Source [SID1234609248]). About Syndesi Therapeutics Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. Its current portfolio fair value is above 150 million . The pharmaceutical industry's most comprehensive news and information delivered every month. This acquisition gives AbbVie access to Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. Syndesi Therapeutics has raised a total of 26.2M in funding over 3 rounds. Though the deal, AbbVie will gain access to Syndesis portfolio of SV2A modulators. We are excited to see Syndesi develop our novel pro-cognitive SV2A modulators to create value for patients with cognitive impairment, said Dhavalkumar Patel, UCBs Chief Scientific Officer and Executive Vice President. AbbVie Acquires Syndesi Therapeutics, Strengthening Neuroscience Portfolio. Founded in 1973, JJDC continues a legacy of customizing deals for data-driven companies across the continuum of healthcare, with the goal of turning great ideas into transformative new pharmaceutical, medical device and consumer healthcare products. This acquisition gives AbbVie access to Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. Privacy Center | Read More Our Science Alkermes Weighs Splitting Off Cancer Biz as Separate, Publicly Traded Company, The 2 Things That Made My Transition to Voice Tech Easier: A Friendly Pricing Model and Easy Implementation, Patient Files Class-action Suit Against Advocate Aurora Health Following Data Breach, Why are Healthcare Costs So High? President of Humanas primary care, Rene Buckingham, addresses the needs of many seniors facing multiple diagnoses and barriers to high-quality care. Syndesi Therapeutics is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. Innovative Med Concepts USA Private Innovative Med Concepts is a biotech company with a pipeline of novel treatments for fibromyalgia and other related . . Bone Therapeutics has a broad portfolio of innovative allogeneic cell therapy solutions across a range of indications. UCB has already developed and commercialized two products that address this target, the epilepsy drugs Keppra and Briviact. About Bone Therapeutics . Important factors that could result in such differences include: changes in general economic, business and competitive conditions, the inability to obtain necessary regulatory approvals or to obtain them on acceptable terms, costs associated with research and development, changes in the prospects for products in the pipeline or under development by UCB, effects of future judicial decisions or governmental investigations, product liability claims, challenges to patent protection for products or product candidates, changes in laws or regulations, exchange rate fluctuations, changes or uncertainties in tax laws or the administration of such laws and hiring and retention of its employees. This acquisition gives AbbVie access to Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. This page shows the latest Syndesi Therapeutics news and features for those working in and with pharma, biotech and healthcare. There is a major unmet need for new therapies that can help improve cognitive function in patients suffering from difficult-to-treat neurologic diseases, Hudson said in a prepared statement. ABOUT HD; ABOUT ALS; NEWS. The companys drugs are small molecules that modulate synaptic transmission, which is the communication that happens between neurons in the brain. You need JavaScript enabled to view it. READ MORE ABOUT US. SIRP-DIRECTED ANTIBODIES IN DEVELOPMENT Our novel monoclonal antibodies are designed to change the lives of patients with immunological diseases and cancer. In June last year, AbbVie exercised an exclusive option for the acquisition of TeneoOne, a Teneobiosubsidiary. They are also entitled to get further contingent payments of up to $870m on meeting specific pre-set milestones. var prefix = 'ma' + 'il' + 'to'; SRIW Socit Rgionale d'Investissement de Wallonie (www.sriw.be) provides equity and/or debt to companies that generate added value and employment in Wallonia. Johnson & Johnson Innovation JJDC Inc. (JJDC) is the strategic venture capital arm of Johnson & Johnson and a long-term investment partner to global healthcare entrepreneurs. AbbVies neuroscience drug prospects are from its partnership with Calico Life Sciences, a firm founded by Google parent company Alphabet. Milestone payments could bring shareholders of the biotech up to $870 million more. About Syndesi Therapeutics Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. COPENHAGEN, Denmark, March 1, 2022 /PRNewswire/ -- Novo Holdings, a leading international life sciences investor, today announces that its portfolio company Syndesi Therapeutics ('Syndesi'). "With AbbVie's acquisition of Syndesi, we aim to advance the research of a novel, first-in-class asset for the potential treatment of cognitive impairment associated with neuropsychiatric and neurodegenerative disorders.". Syndesi Therapeutics offers modulators to improve cognition in diseases such as alzheimer's disease and other conditions causing cognitive impairment. Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. About Syndesi Therapeutics . Syndesi is investigating the potential of these molecules to improve cognition in diseases such as Alzheimer's Disease and other dementias, as well as other conditions such as major depression and cognitive impairment associated with schizophrenia. The objective of the fund is to invest in the development of start-ups, from validation of the technology to commercial maturity. When it comes to contacting clinicians and patients, the hospital switchboard can be just as [], AbbVie, alzheimer's disease, Clinical Trials, deals, life sciences M&A, neuroscience, North Chicago, UCB. Established in 2017, Syndesi focuses on developing new treatments that regulate synaptic activity to alleviate cognitive impairment symptoms. Cognitive impairment observed in various neuropsychiatric and neurodegenerative ailments is claimed to be triggered by synaptic dysfunction. The lead molecule, SDI-118, is a small molecule currently in Phase 1b studies, which is being evaluated to target nerve terminals to enhance synaptic efficiency. Syndesi Therapeutics is developing molecules which act in a unique way on the synaptic vesicle protein SV2A. Syndesi, which is based in Belgium, aims to treat brain disorders by reducing the symptoms of cognitive impairment. Laboratoriumtechnoloog (m/v) VIB Nucleomics Core, Emerging Applications of Microbes (2nd edition), Type 2 Immunity in Homeostasis and Disease (2nd edition). AbbVie has bolstered its neuropsychiatric and neurodegenerative portfolio with the acquisition of Belgium-based Syndesi Therapeutics in a deal valued at up to $1 billion. UCB Ventures is a 150 million strategic corporate venture fund established in 2017 to further strengthen UCB's ability to create value from novel insights and technologies that can transform the lives of patients suffering from severe diseases. . The mechanism is currently being evaluated . AbbVie will pay Syndesi's shareholders a $130 million upfront payment with the potential for Syndesi's shareholders to receive additional contingent payments of up to $870 million based on the achievement of certain predetermined milestones. . document.getElementById('cloak45869').innerHTML += '' + addy45869+'<\/a>'; var addy45869 = 'info' + '@'; According to the deal, shareholders of Syndesi will receive an upfront payment of $130m from AbbVie. North Chicago, Illinois-based AbbVie announced Tuesday that it paid $130 million up front to acquire Syndesi Therapeutics. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. The total value of the deal could. Anthos Therapeutics is a clinical-stage biopharmaceutical company focused on the development and commercialization of genetically and pharmacologically validated innovative therapies to advance care for people living with cardiovascular and metabolic (CVM) diseases. The Company's approach is aimed at treating Alzheimer's Disease and other disorders with cognitive impairment. The biotech notes that disruption of the synaptic connectivity is found in Alzheimers and other types of dementia. Within the life science sector, specific areas of interest to Fountain include specialty pharma, medical devices, biotechnology and diagnostics. About Syndesi Therapeutics Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment.

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